Relative Hyperproteinaemia

this category, the actual amount of protein in your body hasn't gone up, but the fluid volume of the blood has decreased. Because there is less water to dilute them, the concentration of proteins spikes.

​Dehydration:

​Why it happens: If a person loses a significant amount of body water (due to severe vomiting, diarrhea, excessive sweating, or not drinking enough fluids), the plasma volume drops. The total amount of protein stays the same, but it is now packed into a much smaller volume of water, making blood tests show high protein levels.

​Haemoconcentration during Venepuncture:

​Why it happens: This is a localized, artificial form of hemoconcentration. If a healthcare worker leaves a tourniquet on for too long while drawing blood, the pressure forces water and small molecules to leak out of the blood vessels and into the tissues. The larger proteins and blood cells get left behind, crowded together in the remaining blood sample, skewing the lab results.